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Successful Transcatheter Tricuspid Valve Replacement 30 Years After Heart Transplantation
Mateusz Orzalkiewicz1, Tullio Palmerini1, Elena Biagini2
1Interventional Cardiology Unit, IRCCS University Hospital of Bologna, Policlinico S. Orsola, Bologna, Italy.
JACC. Case Reports
|December 4, 2025
Summary
Transcatheter tricuspid valve replacement (TTVR) offers a new solution for severe tricuspid regurgitation (TR) after heart transplantation (HTx). This case demonstrates the first successful TTVR in a heart transplant recipient, showing improved symptoms and prosthesis function.
Area of Science:
- Cardiology
- Cardiac Surgery
- Transplantation Medicine
Background:
- Tricuspid regurgitation (TR) is a frequent complication post-heart transplantation (HTx).
- Managing TR in HTx patients presents significant clinical challenges.

