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Related Experiment Video

Updated: Jul 7, 2026

Encapsulating Cytochrome c in Silica Aerogel Nanoarchitectures without Metal Nanoparticles while Retaining Gas-phase Bioactivity

Encapsulating Cytochrome c in Silica Aerogel Nanoarchitectures without Metal Nanoparticles while Retaining Gas-phase Bioactivity

Published on: March 1, 2016

Multifunctional Plasmonic/Metal-Organic Framework Biohybrid Aerogels.

Yixuan Wang¹, Jingyao Li², Prashant Gupta¹

¹Department of Mechanical Engineering and Materials Science; Institute of Materials Science and Engineering, Washington University in St. Louis, St. Louis, Missouri 63130, United States.

|December 4, 2025

Summary

This summary is machine-generated.

This study presents a new method for creating multifunctional metal-organic framework (MOF) aerogels. These advanced materials offer sensitive detection of toxic chemicals and potent antimicrobial activity.

Keywords:

bacterial nanocellulose (BNC)biohybrid collagen foam metal−organic framework (MOF)plasmonic aerogel

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Area of Science:

Materials Science
Nanotechnology
Chemical Engineering

Background:

Metal-organic frameworks (MOFs) offer tunable properties for various applications.
Developing multifunctional materials with combined sensing and antimicrobial capabilities is a key challenge.
Aerogels provide high surface area and porosity, beneficial for material performance.

Purpose of the Study:

To fabricate self-supporting MOF aerogels using a biotemplated in situ growth method.
To integrate plasmonic nanostructures with MOFs for enhanced functionalities.
To demonstrate the dual capability of these hybrid aerogels for sensing and antimicrobial applications.

Main Methods:

Utilized bacterial nanocellulose (BNC) and collagen foam as biotemplates for MOF growth.
Employed a one-step synthesis for uniform coating of ZIF-8 and ZIF-L MOF crystals.
Incorporated plasmonic nanostructures into the MOF aerogel matrix.

Main Results:

Achieved interconnected 3D open porous MOF aerogels with uniform crystal distribution.
Demonstrated highly sensitive vapor-phase detection of toxic volatile organics (TVOs) via SERS.
Exhibited significant antibacterial efficacy (>99%) against E. coli and S. aureus through photothermal effects and ion release.

Conclusions:

The biotemplated method successfully created multifunctional plasmonic/MOF hybrid aerogels.
These aerogels exhibit synergistic sensing and antimicrobial properties.
The scalable method can be applied to develop advanced 3D porous materials for diverse applications.