Lung infection in orally inoculated SARS-CoV-2 hamsters
Evelyne Picard-Meyer1, Marine Wasniewski1, Franck Boué1
1Nancy Laboratory for Rabies and Wildlife, ANSES, INTERFAS Unit, Malzeville, France.
Abstract:
The digestive tropism of SARS-CoV-2 due to the presence of the same ACE2 receptor in the digestive system as in the respiratory system raised the question of the role of fecal-oral transmission in the pandemic. The aim of this study was to explore oral infection in hamsters model. SARS-CoV-2 inoculation via the oral and intranasal routes resulted in comparable infection in hamsters. In addition to implications for human health, oral infection could have implications for potential animal reservoirs.
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