Efficacy of latanoprost in the treatment of ciliary madarosis

Ciliary madarosis, characterized by the partial or complete loss of eyelashes, has limited treatment options, especially in pediatric cases. Prostaglandin analogues, primarily used in glaucoma treatment, have shown potential as a novel approach for promoting eyelash regrowth due to their hypertrichotic effects. We report the case of a 5-year-old boy presenting with isolated eyelash loss on the right upper eyelid. Following unremarkable systemic and ophthalmologic evaluations, the child was treated with nightly latanoprost 0.005% eye drops applied to the eyelid margin. After three months, eyelash regrowth was observed, with no adverse effects. This case highlights the potential of latanoprost as a viable treatment for pediatric ciliary madarosis. Further research is warranted to establish guidelines for its off-label use in eyelash loss.