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Updated: Jan 9, 2026

Bidirectional Electrical and Optoelectronic Interfaces in Healthy and Ischemic Ex Vivo Rat Hearts
Published on: July 18, 2025
Stormy rhythms: unmasking the heart's electrical storm
Shahrukh Hashmani1, Mokhtar Ibrahim2, Giovanni Mariscalco3
1Department of Cardiology, Royal Brompton Hospital, London, England, UK drshahrukhhashmani@gmail.com.
Ventricular aneurysm resection effectively treated incessant ventricular tachycardia (VT) in a patient refractory to other therapies. This surgical approach improved cardiac function and eliminated VT recurrence.
Area of Science:
- Cardiology
- Cardiac Surgery
- Electrophysiology
Background:
- A 70-year-old male with a history of myocardial infarction and left ventricular (LV) dysfunction presented with ventricular tachycardia (VT).
- Initial treatments including cardioversion, implantable cardioverter-defibrillator, antiarrhythmic drugs, and catheter ablation failed to resolve recurrent VT originating from the LV apex.
- A thrombus was identified at the LV apex, complicating the VT substrate.
Purpose of the Study:
- To evaluate the efficacy of ventricular aneurysectomy as a treatment for incessant VT in a patient with complex cardiac history.
- To explore surgical intervention when medical and catheter-based therapies are insufficient.
Main Methods:
- A multidisciplinary team considered various treatment options, including advanced ablation techniques, radiotherapy, and autonomic modulation.
- The patient underwent coronary artery bypass grafting combined with LV aneurysectomy.
- Postoperative follow-up included clinical assessment and echocardiography.
Main Results:
- The patient experienced significant clinical improvement following surgery.
- No recurrent VT episodes were observed during a 10-month follow-up period.
- Left ventricular ejection fraction increased to 40% postoperatively.
Conclusions:
- Ventricular aneurysectomy, in conjunction with coronary artery bypass grafting, is a viable and effective treatment for incessant VT.
- Surgical resection of the ventricular aneurysm successfully addressed the VT source when other methods failed.
- This case underscores the importance of considering surgical options for refractory VT associated with LV abnormalities.
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