Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Targeted Cancer Therapies02:57

Targeted Cancer Therapies

8.6K
The targeted cancer therapies, also known as “molecular targeted therapies,” take advantage of the molecular and genetic differences between the cancer cells and the normal cells. It needs a thorough understanding of the cancer cells to develop drugs that can target specific molecular aspects that drive the growth, progression, and spread of cancer cells without affecting the growth and survival of other normal cells in the body.
There are several types of targeted therapies against...
8.6K
Issues And Trends In Healthcare Delivery System01:29

Issues And Trends In Healthcare Delivery System

6.1K
The issues and trends in healthcare delivery are constantly changing. The COVID-19 pandemic is one recent issue that wreaked havoc on healthcare systems, causing a shortage of healthcare workers, high demand for medicines and supplies, and increased medical expenditure due to a lack of insurance. Other issues include rising healthcare costs and care fragmentation.
Cost Containment
Payment for healthcare services has historically promoted adoption of costly and often unnecessary or inefficient...
6.1K
Cancer Therapies02:49

Cancer Therapies

9.8K
Cancer therapies are various modes of treatment, such as surgery, radiation therapy, and chemotherapy that are administered to cancer patients.
However, cancer treatments can pose several challenges, as therapies used to kill cancer cells are generally also toxic to normal cells. Moreover, cancer cells mutate rapidly and can develop resistance to chemical agents or radiation therapy. Besides, all types of cancer cells may not respond to the same therapy. Some cancer cells respond to one...
9.8K
Tumor Immunotherapy01:27

Tumor Immunotherapy

1.7K
Immunotherapy is a treatment that boosts or manipulates the immune system to fight diseases, including cancer. For instance, by stimulating an immune response through vaccinations against viruses that cause cancers, like hepatitis B virus and human papillomavirus, these diseases can be prevented. Nonetheless, some cancer cells can avoid the immune system due to their rapid mutation and division. The immune response to many cancers involves three phases: elimination, equilibrium, and escape.
1.7K
Treatment Resistant Cancers02:56

Treatment Resistant Cancers

3.7K
Cancer is the second leading cause of death in the United States. A cancer cell is genetically unstable and hence can mutate faster. They can also modify their microenvironment and escape immune surveillance. The difficulties in treating cancer are further compounded by the emergence of rapid resistance to anticancer drugs. The most common ways to attain resistance in cancer cells include alteration in drug transport and metabolism, modification of drug target, elevated DNA damage response, or...
3.7K
Microorganisms in Medicine and Therapeutics01:29

Microorganisms in Medicine and Therapeutics

917
Microorganisms play a fundamental role in vaccine development, gene therapy, and therapeutic production. Their biological properties are harnessed to advance medicine and public health. Beyond immunization, microorganisms contribute to gut health, antibiotic synthesis, and genetic disease treatment.Live Attenuated and Inactivated VaccinesLive attenuated vaccines, such as the measles, mumps, and rubella (MMR) vaccine, utilize weakened forms of pathogens to closely resemble natural infections.
917

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

A Year of Growth, Change, and Momentum.

Journal of nuclear medicine technology·2026
Same author

A Magnetic Resonance-Compatible Fiberoptic Temperature Sensor for Measuring Focused Ultrasound-Induced Heating Without Artifacts.

Ultrasound in medicine & biology·2026
Same author

Neuroimaging Today: Science, Practice, and the Path Forward.

Journal of nuclear medicine technology·2026
Same author

Strategic Growth and Global Impact: The SNMMI Technologist Section Looks Ahead.

Journal of nuclear medicine technology·2026
Same author

Brain Primer, Part 2: Pathophysiology of Neurodegeneration.

Journal of nuclear medicine technology·2026
Same author

Brain Primer, Part 1: The Neuroanatomy and Physiology Behind Memory and Aging.

Journal of nuclear medicine technology·2026

Related Experiment Video

Updated: Jan 9, 2026

Surface-enhanced Resonance Raman Scattering Nanoprobe Ratiometry for Detecting Microscopic Ovarian Cancer via Folate Receptor Targeting
07:54

Surface-enhanced Resonance Raman Scattering Nanoprobe Ratiometry for Detecting Microscopic Ovarian Cancer via Folate Receptor Targeting

Published on: March 25, 2019

8.6K

Theranostics Beyond Oncology: Emerging Applications.

Sara L Johnson1, Sarah R Gibbons2, Cybil J Nielsen2

  • 1Gurnick Academy of Medical Arts, Concord, California sajohnson@gurnick.edu.

Journal of Nuclear Medicine Technology
|December 4, 2025
PubMed
Summary
This summary is machine-generated.

Theranostics, combining diagnosis and treatment, is expanding beyond cancer to non-cancerous diseases like heart, brain, and autoimmune conditions. Advances in imaging and targeted therapies show great potential but require further clinical validation.

Keywords:
autoimmunitycardiologynanoparticlesradiopharmaceuticalstheranostics

More Related Videos

Radionuclide-fluorescence Reporter Gene Imaging to Track Tumor Progression in Rodent Tumor Models
10:04

Radionuclide-fluorescence Reporter Gene Imaging to Track Tumor Progression in Rodent Tumor Models

Published on: March 13, 2018

12.5K
A Blood-based Test for the Detection of ROS1 and RET Fusion Transcripts from Circulating Ribonucleic Acid Using Digital Polymerase Chain Reaction
10:35

A Blood-based Test for the Detection of ROS1 and RET Fusion Transcripts from Circulating Ribonucleic Acid Using Digital Polymerase Chain Reaction

Published on: April 5, 2018

10.7K

Related Experiment Videos

Last Updated: Jan 9, 2026

Surface-enhanced Resonance Raman Scattering Nanoprobe Ratiometry for Detecting Microscopic Ovarian Cancer via Folate Receptor Targeting
07:54

Surface-enhanced Resonance Raman Scattering Nanoprobe Ratiometry for Detecting Microscopic Ovarian Cancer via Folate Receptor Targeting

Published on: March 25, 2019

8.6K
Radionuclide-fluorescence Reporter Gene Imaging to Track Tumor Progression in Rodent Tumor Models
10:04

Radionuclide-fluorescence Reporter Gene Imaging to Track Tumor Progression in Rodent Tumor Models

Published on: March 13, 2018

12.5K
A Blood-based Test for the Detection of ROS1 and RET Fusion Transcripts from Circulating Ribonucleic Acid Using Digital Polymerase Chain Reaction
10:35

A Blood-based Test for the Detection of ROS1 and RET Fusion Transcripts from Circulating Ribonucleic Acid Using Digital Polymerase Chain Reaction

Published on: April 5, 2018

10.7K

Area of Science:

  • Nuclear Medicine
  • Molecular Imaging
  • Nanotechnology

Background:

  • Theranostics, integrating targeted diagnostics and therapeutics, is evolving beyond oncology.
  • Radiopharmaceuticals, molecular imaging, and nanoparticles are key enabling technologies.

Purpose of the Study:

  • To review emerging non-oncologic applications of theranostics.
  • To highlight current research and future potential in non-cancerous disease treatment.

Main Methods:

  • Review of recent advances in radiopharmaceuticals and molecular imaging.
  • Exploration of nanoparticle-based technologies for targeted delivery.
  • Analysis of theranostic applications in cardiology, neurology, and autoimmune disorders.

Main Results:

  • Theranostics show promise in treating atherosclerosis, cardiac amyloidosis, and Alzheimer disease.
  • Biomarkers like fibroblast activation protein inhibitor and radiolabeled glucocorticoids are utilized in autoimmune diseases.
  • Selective ablation of diseased tissue is explored for bone marrow conditioning.

Conclusions:

  • Theranostic applications are expanding into diverse non-cancerous fields.
  • Challenges include clinical integration and robust efficacy trials.
  • Continued research is vital for realizing the full potential of theranostics in non-oncologic settings.