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The Tumor Microenvironment

The Tumor Microenvironment

Every normal cell or tissue is embedded in a complex local environment called stroma, consisting of different cell types, a basal membrane, and blood vessels. As normal cells mutate and develop into cancer cells, their local environment also changes to allow cancer progression. The tumor microenvironment (TME) consists of a complex cellular matrix of stromal cells and the developing tumor. The cross-talk between cancer cells and surrounding stromal cells is critical to disrupt normal tissue...

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Related Experiment Video

Updated: Jan 9, 2026

Culture of Bladder Cancer Organoids as Precision Medicine Tools

Culture of Bladder Cancer Organoids as Precision Medicine Tools

Published on: December 28, 2021

The Bladder Tumor Microenvironment Is a Dynamic Ecosystem: How Microbes, Immunity, and Cancer Converge

David J McConkey¹, Jennifer J Barb², Armine K Smith³

¹Department of Urology, University of Rochester Medical Center, Rochester, NY, USA; Wilmont Cancer Institute, University of Rochester Medical Center, Rochester, NY, USA.

European Urology

|December 4, 2025

Summary

No abstract available in PubMed .

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