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Methylene blue associated retinal toxicity.

Sidra Zafar1, Martin Calotti2, Timothy T Xu2

  • 1Wills Eye Hospital Retina Service, Mid Atlantic Retina, Thomas Jefferson University, 840 Walnut Street, Suite 1020, Philadelphia, PA, 19107, USA. sidrazafariqbal@gmail.com.

International Journal of Retina and Vitreous
|December 4, 2025
PubMed
Summary
This summary is machine-generated.

Inadvertent use of methylene blue during eye surgery can cause severe retinal toxicity, leading to significant vision loss. Ophthalmologists must exercise caution to prevent accidental administration of this vital dye.

Area of Science:

  • Ophthalmology
  • Retinal Surgery

Background:

  • Epiretinal membrane (ERM) surgery involves pars plana vitrectomy (PPV).
  • Accidental administration of vital dyes can occur during ophthalmic procedures.

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