Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Oogenesis02:07

Oogenesis

68.8K
In human women, oogenesis produces one mature egg cell or ovum for every precursor cell that enters meiosis. This process differs in two unique ways from the equivalent procedure of spermatogenesis in males. First, meiotic divisions during oogenesis are asymmetric, meaning that a large oocyte (containing most of the cytoplasm) and minor polar body are produced as a result of meiosis I, and again following meiosis II. Since only oocytes will go on to form embryos if fertilized, this unequal...
68.8K
Irritable Bowel Syndrome I: Introduction01:17

Irritable Bowel Syndrome I: Introduction

893
Irritable Bowel Syndrome (IBS) is characterized by functional disturbances in the gastrointestinal system, presenting a cluster of symptoms without evident structural or biochemical abnormalities. It primarily affects the large intestine and may cause abdominal pain, bloating, excessive gas, diarrhea, constipation, or both.
IBS is a chronic condition that can persist over a long period or recur frequently.
The pathogenesis of IBS involves a complex interplay of the following factors:
Altered...
893

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Dietary emulsifiers and host inflammation synergistically drive genomic evolution of Crohn's disease-associated Escherichia coli toward enhanced pathogenicity.

Journal of Crohn's & colitis·2026
Same author

Microbial metabolites at the front line: Orchestrating gastrointestinal and systemic barrier immunity across the lifespan.

Cell reports·2026
Same author

Soil-derived microbiota induces T regulatory cells and protect against mouse colitis, metabolic disease, and sepsis.

Gut microbes·2026
Same author

Food Coloring Additives and Incidence of Type 2 Diabetes in the NutriNet-Santé Prospective Cohort.

Diabetes care·2026
Same author

Preservative food additives, hypertension, and cardiovascular diseases: the NutriNet-Santé study.

European heart journal·2026
Same author

Microbial metabolite Enterobactin impairs mitochondrial respiration and alleviates colitis.

Gut microbes·2026

Related Experiment Video

Updated: Jan 9, 2026

Establishment of an Experimental Mouse Model of Endometrioma to Study its Related Infertility
08:07

Establishment of an Experimental Mouse Model of Endometrioma to Study its Related Infertility

Published on: April 5, 2024

1.4K

Microbiota insights in endometriosis.

Guillaume Parpex1,2,3, Carole Nicco4, Benoît Chassaing5,6

  • 1Université Paris-Cité, Paris, France. guillaume.parpex@aphp.fr.

Microbiome
|December 4, 2025
PubMed
Summary

Endometriosis, a condition affecting 10% of women, involves immune dysfunction and gut microbiota changes. This review explores the gut, endometrial, and gynecological microbiota

Keywords:
EndometriosisGut microbiotaGynecological microbiotaHost-microbe interactionMetabolites

More Related Videos

Characterization and Functional Prediction of Bacteria in Ovarian Tissues
10:12

Characterization and Functional Prediction of Bacteria in Ovarian Tissues

Published on: October 23, 2021

3.2K
Intraoperative Detection of Subtle Endometriosis: A Novel Paradigm for Detection and Treatment of Pelvic Pain Associated with the Loss of Peritoneal Integrity
07:20

Intraoperative Detection of Subtle Endometriosis: A Novel Paradigm for Detection and Treatment of Pelvic Pain Associated with the Loss of Peritoneal Integrity

Published on: December 21, 2012

16.4K

Related Experiment Videos

Last Updated: Jan 9, 2026

Establishment of an Experimental Mouse Model of Endometrioma to Study its Related Infertility
08:07

Establishment of an Experimental Mouse Model of Endometrioma to Study its Related Infertility

Published on: April 5, 2024

1.4K
Characterization and Functional Prediction of Bacteria in Ovarian Tissues
10:12

Characterization and Functional Prediction of Bacteria in Ovarian Tissues

Published on: October 23, 2021

3.2K
Intraoperative Detection of Subtle Endometriosis: A Novel Paradigm for Detection and Treatment of Pelvic Pain Associated with the Loss of Peritoneal Integrity
07:20

Intraoperative Detection of Subtle Endometriosis: A Novel Paradigm for Detection and Treatment of Pelvic Pain Associated with the Loss of Peritoneal Integrity

Published on: December 21, 2012

16.4K

Area of Science:

  • Reproductive immunology
  • Microbiome research
  • Gynecology

Background:

  • Endometriosis affects 10% of reproductive-age women, causing pain and infertility.
  • It's increasingly viewed as a systemic, immune-mediated condition with complex origins.
  • Digestive symptoms are common, suggesting a link to gut microbiota alterations.

Purpose of the Study:

  • To provide a comprehensive overview of endometriosis, focusing on pathophysiology and clinical features.
  • To review the relationship between endometriosis, immune dysregulation, and the gut microbiota.
  • To discuss emerging research on endometrial and gynecological microbiomes and novel microbiota-targeted therapies.

Main Methods:

  • Narrative review of animal and human studies.
  • Analysis of research on gut, endometrial, and vaginal microbiomes.
  • Exploration of immune dysregulation and its link to microbiota.

Main Results:

  • Endometriosis is associated with significant immune dysregulation.
  • Alterations in gut microbiota are frequently observed in patients.
  • The endometrial and gynecological microbiomes are increasingly recognized for their role.

Conclusions:

  • Endometriosis is a complex, multifactorial disease with systemic immune and microbiota involvement.
  • Microbiota-targeted therapies represent a promising avenue for future endometriosis management.
  • Further research into the interplay between host immunity and microbial communities is crucial.