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Refractory Status Epilepticus Treated With Bilateral Pulvinar Deep Brain Stimulation-A Case Study
Mengxuan Tang1, Amerta Bai1, Felipe Rodridgues Marques Ferreira1
1Department of Neurology, University of Minnesota Medical Center, Minneapolis, Minnesota, USA.
Annals of Clinical and Translational Neurology
|December 5, 2025
Summary
New-onset refractory status epilepticus (NORSE) is a severe condition. Targeting thalamic pulvinar nuclei with sensing-enabled deep brain stimulation (DBS) improved seizure burden in a refractory case.
Area of Science:
- Neurology
- Neurosurgery
- Epileptology
Background:
- New-onset refractory status epilepticus (NORSE) presents a critical challenge with high mortality and morbidity.
- Established treatments including anti-seizure medications, anesthetics, and immunomodulation often prove insufficient.
- Deep brain stimulation (DBS) targeting specific thalamic nuclei shows potential for refractory cases.
