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Efficacy of Tofacitinib in Alopecia Areata - Lucky Punch or Robust Treatment Option?

Merian Ranjbaryan1, Peter Weisenseel1, Syrus Alexander Karsai1,2

  • 1Department of Dermatology, Dermatologikum Hamburg, Hamburg, Germany.

International Journal of Trichology
|December 5, 2025
PubMed

Insights

This case study highlights a patient with alopecia areata who found success with tofacitinib after treatments with Baricitinib and Abrocitinib failed. Tofacitinib may be a future treatment option for alopecia areata.

Area of Science:

  • Dermatology
  • Immunology
  • Pharmacology

Background:

  • Alopecia areata is an autoimmune condition causing hair loss.
  • Janus kinase (JAK) inhibitors are emerging treatments for alopecia areata.
  • Previous JAK inhibitors (Baricitinib, Abrocitinib) were ineffective for this patient.
Keywords:
AbrocitinibJanus kinase-inhibitoralopecia areatabaricitinibtofacitinib

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