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Dressing-induced allergic contact dermatitis in total joint arthroplasty
Farouk Khury1,2,3, Garrett Ruff4, Sophia Antonioli4
1Technion Israel Institute of Technology, Haifa, Israel. farouk.khury@technion.ac.il.
International Orthopaedics
|December 5, 2025
Summary
Dressing-induced allergic contact dermatitis (DIACD) after joint replacement surgery is rare (0.3%), often linked to mesh-adhesive dressings. Non-smokers and those undergoing knee replacement are at higher risk.
Area of Science:
- Orthopedic Surgery
- Dermatology
- Allergy and Immunology
Background:
- Dressing-induced allergic contact dermatitis (DIACD) is a potential complication following orthopedic procedures.
- Understanding the incidence and risk factors for DIACD after total hip arthroplasty (THA) and total knee arthroplasty (TKA) is crucial for patient care.
Purpose of the Study:
- To determine the incidence of DIACD after THA and TKA.
- To identify risk factors associated with DIACD, including dressing types and patient characteristics.
Main Methods:
- Retrospective review of patients undergoing primary THA or TKA between 2019 and 2024.
- Analysis of medical records for DIACD diagnoses, medication use, patient demographics, and dressing exposures.
Main Results:
- A low incidence of 0.3% (61/23,396) for DIACD was observed, typically occurring around two weeks postoperatively.
- Mesh-adhesive dressings were most frequently implicated (41%).
- Higher risk was associated with TKA and never smoking, though effect sizes were negligible.
Conclusions:
- DIACD following joint arthroplasty is uncommon but clinically relevant.
- Mesh-adhesive dressings are the primary culprits, and prior dressing exposure may increase risk.
- Identifying patients undergoing TKA and non-smokers can help tailor dressing choices to mitigate DIACD risk.
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