Core Interventions for the Prevention of Peritoneal Dialysis-Related Infections

Area of Science:

• Nephrology
• Infectious Disease Prevention
• Dialysis Technology

Background:

• Peritoneal dialysis (PD) offers advantages over hemodialysis (HD) but carries risks of infection, including peritonitis and catheter-site infections.
• These infections are a significant cause of morbidity, mortality, and transfer from PD, with wide variations in prevention practices across facilities.
• Addressing these challenges is crucial for improving patient quality of life and supporting the expansion of home dialysis.

Purpose of the Study:

• To develop and propose standardized core interventions for reducing PD-related infections in U.S. dialysis facilities.
• To establish evidence-based strategies for consistent infection prevention and monitoring.
• To enhance patient outcomes and support the growth of home dialysis modalities.

Main Methods:

• Facilitation of a workgroup by the American Society of Nephrology (ASN) to develop core interventions.
• Incorporation of expert review and feedback through an iterative process.
• Development of six key strategies based on evidence and international guidelines.

Main Results:

• Six core intervention strategies were identified: surveillance and feedback, standardized staff training, patient education, infection prevention assessments, and antimicrobial prophylaxis.
• Emphasis on consistency in implementation and monitoring at the facility level.
• The interventions aim to reduce infection risks and improve quality of life for PD patients.

Conclusions:

• Standardized interventions are essential for reducing PD-related infections and improving patient outcomes.
• Effective implementation requires coordinated efforts among healthcare teams, patients, and support networks.
• Ongoing research and quality improvement initiatives are necessary to refine practices and address future challenges in PD infection prevention.