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Subungual Reactive Eccrine Syringofibroadenoma: A Case Report.

Carolina Areán1, David Revilla2, Román Miñano2

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Summary

Eccrine syringofibroadenoma, often a reactive hyperplasia of eccrine ducts, rarely occurs in the subungual location. Recognizing its subtle histopathological findings is crucial for accurate diagnosis.

Keywords:
Mascaróeccrinesubungualsyringofibroadenoma

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Area of Science:

  • Dermatopathology
  • Histopathology

Background:

  • Eccrine syringofibroadenoma (ES) was first described in 1963.
  • Later studies suggest ES is a hyperplasia of eccrine ducts, not a true neoplasm, often associated with various dermal alterations.

Purpose of the Study:

  • To highlight the rare subungual location of eccrine syringofibroadenoma.
  • To emphasize the importance of including ES in differential diagnoses for subungual lesions.

Main Methods:

  • Review of literature on eccrine syringofibroadenoma.
  • Analysis of histopathological findings in subungual lesions.

Main Results:

  • Eccrine syringofibroadenoma is infrequently reported in the subungual area.
  • Histopathological features can be subtle and easily overlooked.

Conclusions:

  • Subungual eccrine syringofibroadenoma requires careful histopathological evaluation.
  • Increased awareness can prevent misdiagnosis and diagnostic uncertainty.