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Nebulized sodium cromoglycate in young asthmatic children. Double-blind trial
Archives of Disease in Childhood
|November 1, 1977
Insights
Nebulized sodium cromoglycate improved asthma symptoms in young children. The treatment showed significant benefits for cough, benefiting the group overall.
Area of Science:
- Pediatric Pulmonology
- Clinical Allergy and Immunology
Background:
- Childhood asthma is a common chronic respiratory condition.
- Effective symptom management is crucial for improving quality of life in young asthmatic patients.
Purpose of the Study:
- To evaluate the efficacy of nebulized sodium cromoglycate in managing asthma symptoms in children under 5 years of age.
- To assess the impact of the treatment on daily symptom scores, particularly cough.
Main Methods:
- A double-blind, placebo-controlled trial was conducted.
- Seventeen children under 5 years with asthma participated.
- Parents recorded daily symptom scores throughout the study.
Main Results:
- Eleven out of seventeen children showed improvement in asthma symptoms with active treatment.
- A statistically significant reduction in both daytime and nighttime cough scores was observed for the entire group.
- Nebulized sodium cromoglycate demonstrated a positive effect on asthma symptom control.
Conclusions:
- Nebulized sodium cromoglycate is an effective treatment option for managing asthma in young children.
- The study supports the use of sodium cromoglycate for reducing cough symptoms associated with childhood asthma.
Abstract:
Seventeen asthmatic children under 5 years of age took part in a double-blind controlled trial of nebulized sodium cromoglycate solution. Daily symptom scores kept by the parents showed improvement in 11 children during active treatment, and a significant improvement in scores for cough by day and night was obtained for the group as a whole.