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Capture first, then deliver!

Iktae Kim1, Jeong-Yong Suh2

  • 1Research Institute of Agriculture and Life Sciences, Seoul National University, Seoul 08826, Korea.

Structure (London, England : 1993)
|December 5, 2025
PubMed
Summary

The Cas1-Cas2/3 integrase complex undergoes significant structural changes upon binding foreign DNA. This rearrangement is crucial for delivering prespacer DNA to the CRISPR array, a key step in immunity.

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