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Drug-Induced Senescence in Liver Cells Promotes M2 Macrophage Polarization: Implications for Tyrosine Kinase Inhibitor-Associated Hepatotoxicity

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(-)-Guaiol Downregulates M2 Tumor-Associated Macrophage Polarization Through PPAR-γ Signaling to Suppress Lung Cancer

Zhen-Yu Zhao1, Jian-Chun Wu1, Ying-Bin Luo1

  • 1Clinical Medical Center of Oncology, Shanghai Municipal Hospital of Traditional Chinese Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai, 200071, China.

Biological Procedures Online
|December 5, 2025
PubMed
Abstract

No abstract available in PubMed .

Keywords:
(-)-GuaiolCD36CPT1Lewis lung cancerPPAR-γ

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