Related Experiment Video
Updated: Jan 9, 2026

Using 2-Photon Microscopy to Quantify the Effects of Chronic Unilateral Ureteral Obstruction on Glomerular Processes
Published on: March 4, 2022
Advances in multi-omics and therapeutic studies of Henoch-Schönlein purpura
Mengyan Xu1, Zhuohang Wei1, Lu Wang1
1School of Public Health & Key Laboratory of Tropical Translational Medicine of Ministry of Education, Hainan Medical University, Haikou, 571199, China.
Abstract:
Henoch-Schönlein purpura (HSP) is a vasculopathic disease due to lesions in blood vessels, and patients with HSP presenting with renal injury are at risk of further progression to end-stage renal disease, resulting in a severe disease burden, the pathogenesis of which is currently unclear. By integrating multi-omics data, biomarkers and signaling pathways that are specifically expressed in HSP can be screened, thus finding new perspectives for resolving the pathogenesis of HSP. The aim of this review is to explore the developmental pathways of HSP and to reveal key biomarkers and therapeutic targets. Finally, we discuss the therapeutic approaches to HSP, with the hope that these insights will drive the future development of personalized medicine and improve patient prognosis and quality of life.
More Related Videos
Related Concept Videos
Nephrotic Syndrome II : Assessment and Medical Management
Acute Kidney Injury IV: Diagnostic Studies and Prevention
Rheumatic Heart Disease II: Clinical Manifestations and Diagnostic Studies
Acute Pyelonephritis II: Diagnostic Studies and Management
Nephrotic Syndrome I : Introduction

