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Updated: Jan 9, 2026
05:33
Introduction of an Integrated Pathology Image Management, Artificial Intelligence, and Reporting System
Published on: July 11, 2025
752
Whole Slide Imaging in Genitourinary Pathology: A Cloud-Based Digitisation Workflow for Resource-Limited Settings
Aisha Memon1, Talat Zehra2, Sarosh Moeen1
1Department of Pathology and Laboratory Medicine, The Aga Khan University Hospital, Karachi, Pakistan.
Journal of the College of Physicians and Surgeons--Pakistan : JCPSP
|December 6, 2025
Summary
Digitizing genitourinary glass slides into whole-slide images (WSIs) enables research and education. This method facilitates improved diagnostic consensus, particularly in resource-limited settings, via accessible digital formats.
Area of Science:
- Pathology
- Digital Health
- Medical Imaging
Background:
- Genitourinary pathology traditionally relies on physical glass slides.
- Digitization offers potential for enhanced research, education, and knowledge sharing.
- Telepathology and digital image interpretation are emerging fields.
Purpose of the Study:
- To digitize genitourinary glass slides for research, education, and knowledge sharing.
- To evaluate the utility of whole-slide images (WSIs) generated from digitized slides.
- To assess the feasibility of using digital pathology in resource-limited settings.
Main Methods:
- An observational study was conducted using 31 renal biopsy cores and 21 prostate tissue cores.
- Videos of stained slides were recorded and uploaded to an open-source platform to create WSIs.
- Three pathologists independently reviewed the WSIs, with inter-observer agreement assessed using the Kappa statistic.
Main Results:
- Pathologist A achieved 100% agreement with reference diagnoses for renal stains.
- Pathologist B showed 77% concordance for H&E and 74% for other stains.
- Pathologist C reported high agreement (74-100%) across different stains for both renal and prostate biopsies.
Conclusions:
- Whole-slide images (WSIs) are viewable via shareable links, including on smartphones.
- Digitization aids in achieving consensus on diagnoses, benefiting resource-limited areas.
- Digital pathology platforms can enhance collaboration and diagnostic accuracy in genitourinary pathology.
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