Related Experiment Video
Updated: Jan 7, 2026
Assessment of Intestinal Transcytosis of Neonatal Escherichia coli Bacteremia Isolates
Published on: February 17, 2023
Clinicoepidemiological Characteristics of Recurrent Intussusception Among Children Younger than 2 Years Hospitalized
Varsha Sudhir Chaudhary1, Anupama Machathi1, Namrata Kharat1
1Department of Community Medicine, Christian Medical College, Vellore, Tamil Nadu, 632002, India.
Insights
Recurrent intussusception in children is more common in Kerala, India. Crying and irritability are key indicators, necessitating region-specific treatment protocols.
Area of Science:
- Pediatric Gastroenterology
- Clinical Epidemiology
- Public Health
Background:
- Intussusception is a common pediatric surgical emergency.
- Recurrence rates and associated risk factors require further investigation, particularly in diverse geographical settings.
Purpose of the Study:
- To determine the incidence of recurrent intussusception in children in southern and western India.
- To identify clinical and epidemiological risk factors linked to intussusception recurrence.
Main Methods:
- A multicenter observational study involving 1,406 children under 2 years with intussusception across four Indian states.
- Data collection included clinical, epidemiological, and sociodemographic factors via questionnaires and medical records.
- Follow-up assessed recurrence rates and vital status.
Main Results:
- The overall recurrence rate was 4.2% (55/1,406), with a median time to first recurrence of 137 days.
- Recurrence incidence was significantly higher in Kerala (5.7%) compared to other states (2.4%).
- Incessant crying/irritability and radiological reduction were more frequent in recurrent cases.
Conclusions:
- Regional disparities in intussusception recurrence exist, with Kerala showing a higher incidence.
- Clinical factors like crying and irritability are associated with recurrence.
- Region-specific protocols are needed to optimize management and reduce recurrence rates.
Objectives:
To assess the incidence of recurrent episodes of intussusception in children in southern and western India and identify risk factors associated with recurrence.
Methods:
This multicenter observational study was conducted from August 2019 to December 2022 in children with intussusception aged under 2 y admitted to 21 hospitals in four Indian states: Kerala and Karnataka in southern India and Maharashtra and Gujarat in western India. Clinical, epidemiological, and sociodemographic data were collected using structured questionnaires, medical records, and radiological reports. A single follow-up was conducted in July 2023 to assess vital status and the incidence of intussusception recurrence.
Results:
Out of the 1,406 children enrolled with intussusception, 85 were unavailable for follow-up and 55 (4.2%) experienced one or more recurrent episodes during the study period. The median time to the first recurrence was 137 d. The incidence of recurrence was significantly higher in Kerala (40/697; 5.7%) than in the other three states (15/624; 2.4%; p = 0.027). Incessant crying and irritability were significantly more common in recurrent episodes (20/55; 36.4%) than in first episodes (269/1,266; 21.2%; p = 0.009). Radiological reduction was significantly more common in recurrent cases (49/55; 89.1%) than in first-episode cases (988/1,266; 78%; p = 0.039).
Conclusions:
This study reveals regional and clinical factors associated with recurrence of intussusception and highlights the need for region-specific protocols to optimize treatment and minimize the incidence of recurrence. The reasons for the regional disparities in the incidence of recurrence should be investigated.
More Related Videos
10:57Determining Soil-transmitted Helminth Infection Status and Physical Fitness of School-aged Children
Published on: August 22, 2012
08:23Culture Methods to Determine the Limit of Detection and Survival in Transport Media of Campylobacter Jejuni in Human Fecal Specimens
Published on: March 10, 2020
Related Concept Videos
01:26Esophageal Strictures-II: Clinical Features and Management
Healthcare providers should gather a comprehensive medical history and conduct a physical examination for diagnosis. If esophageal stricture is...
01:30Inflammatory Bowel Disease II: Crohn's Disease
Inflammatory bowel disease, commonly known as IBD, refers to a collection of disorders that lead to persistent inflammation of the gastrointestinal tract. The two types of IBD are ulcerative colitis, which impacts the colon, and Crohn's disease, which can involve any part of the gastrointestinal segment.
Crohn's disease
Crohn's disease is a chronic, systemic inflammatory bowel disease (IBD) that predominantly affects the gastrointestinal tract. It is marked by...
01:30Irritable Bowel Syndrome II: Clinical Features and Diagnostic Evaluation
Irritable Bowel Syndrome (IBS) is classified into subtypes based on the predominant bowel habits as determined by the Bristol Stool Form Scale (BSFS). The subtypes are:
01:30Esophageal Strictures-I: Introduction
Etiology
The primary cause of esophageal strictures is long-standing gastroesophageal reflux disease (GERD), accounting for about 70 to 80% of adult cases. Chronic acid reflux can lead to injury and scarring of the esophageal lining, culminating in...
01:22Appendicitis-I: Introduction
Etiology: Appendicitis can arise from various causes, primarily rooted in the obstruction of the appendix lumen. Factors contributing to this obstruction include fecal accumulation, lymphoid hyperplasia and, in...
01:08Prevalence and Incidence
Prevalence indicates the proportion of individuals in a population who have a specific disease or health...