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Frequency-spatial synergistic network for accelerated multi-contrast MRI reconstruction.

Ke Li1, Dong Liang2, Guoqing Chen1

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Computerized Medical Imaging and Graphics : the Official Journal of the Computerized Medical Imaging Society
|December 7, 2025
PubMed
Summary

The new Multi-Contrast Dual-Domain (MCDD) network accelerates Magnetic Resonance Imaging (MRI) reconstruction by effectively integrating multi-contrast information. This approach significantly improves image quality and reduces artifacts in accelerated MRI scans.

Keywords:
Dual-domain featureFeature fusionMRI reconstructionMulti-contrastPrior learning

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Area of Science:

  • Medical Imaging
  • Biomedical Engineering
  • Computer Vision

Background:

  • Accelerating Magnetic Resonance Imaging (MRI) is crucial for clinical efficiency.
  • Multi-contrast MRI reconstruction utilizes auxiliary modalities to enhance target contrast reconstruction.
  • Key challenges include capturing cross-contrast global dependencies and integrating complementary information.

Purpose of the Study:

  • To propose a novel network, the Multi-Contrast Dual-Domain (MCDD) network, for accelerated multi-contrast MRI reconstruction.
  • To effectively capture global dependencies and integrate complementary information across different MRI contrasts.
  • To improve the quality and efficiency of accelerated MRI scans.

Main Methods:

  • The proposed Multi-Contrast Dual-Domain (MCDD) network leverages frequency-domain information for global dependency capture.
  • It employs a Single-Contrast Learning (SCL) module as a prior to guide a Multi-Contrast Learning (MCL) module.
  • Both modules extract features using Frequency (Fre) and Spatial (Spa) blocks, fused by an Adaptive Fusion Mechanism (AFM).

Main Results:

  • MCDD demonstrated superior performance over state-of-the-art methods on BraTS, MRBrainS, and fastMRI datasets.
  • Achieved significant Peak Signal-to-Noise Ratio (PSNR) improvements: 2.42 dB (4×), 2.11 dB (8×), 1.63 dB (16×), and 0.82 dB (32×).
  • Qualitative results showed enhanced structural fidelity and reduced artifacts in reconstructed MRI images.

Conclusions:

  • The MCDD network is an effective solution for accelerated MRI reconstruction.
  • It successfully addresses the challenges of cross-contrast dependency and information integration.
  • The method offers improved image quality and artifact reduction for faster MRI acquisition.