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The Long-term observation of the quick contrast sensitivity and its influencing factors after SMILE.

Weijung Ten1, Yangyi Huang2, Yiyong Xian2

  • 1Eye Institute and Department of Ophthalmology, Eye & ENT Hospital, Fudan University, Shanghai 200031, China; Key laboratory of Myopia and Related Eye Diseases, NHC; Key laboratory of Myopia and Related Eye Diseases, Chinese Academy of Medical Sciences; Shanghai Research Center of Ophthalmology and Optometry; Shanghai Engineering Research Center of Laser and Autostereoscopic 3D for Vision Care (20DZ2255000); Shanghai Bright Baoshi Eye Hospital, Shanghai 201900, China.

Photodiagnosis and Photodynamic Therapy
|December 7, 2025

View abstract on PubMed

Summary
This summary is machine-generated.

Small Incision Lenticule Extraction (SMILE) shows excellent 7-year outcomes, preserving visual quality. Factors like corneal thickness and residual astigmatism influence long-term contrast sensitivity after SMILE vision correction.

Keywords:
DecentrationEOZHigh myopiaSMILE

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Area of Science:

  • Ophthalmology
  • Refractive Surgery
  • Corneal Surgery

Background:

  • Small Incision Lenticule Extraction (SMILE) is a popular refractive surgery.
  • Long-term effects of SMILE on visual quality metrics like contrast sensitivity require further investigation.

Purpose of the Study:

  • To investigate the 7-year impact of SMILE on quantitative contrast sensitivity (qCSF).
  • To identify determinants of long-term qCSF after SMILE.

Main Methods:

  • 80 eyes (mean spherical equivalent -6.10±1.95 D) underwent SMILE.
  • Postoperative assessments at 7 years included refraction, axial length, corneal topography, and qCSF.
  • Correlations between qCSF and ocular parameters like decentration and effective optical zone (EOZ) were analyzed.
qCSF

Main Results:

  • SMILE surgeries were uncomplicated with good safety and efficacy indices.
  • Correlations found between cylindrical refraction (CR), residual CR, and qCSF.
  • Lower ablation, higher initial CR, and lower residual CR were associated with superior qCSF.
  • Long-term decentration negatively impacted qCSF in high myopia.

Conclusions:

  • SMILE demonstrated excellent 7-year outcomes with high uncorrected distant visual acuity (UDVA).
  • Preservation of corneal thickness correlated with better postoperative contrast sensitivity.
  • Residual astigmatism and minor decentration were linked to slightly reduced long-term outcomes.