Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Field Effect Transistor

Field Effect Transistor

Field-effect transistors (FETs) are integral to electronic circuits and distinguished by their three-terminal setup: the gate, drain, and source. These transistors operate as unipolar devices, which utilize either electrons or holes as charge carriers, in contrast to bipolar transistors, which use both types of carriers. The primary function of the FET is to modulate the flow of these carriers from the source to the drain through a channel. The voltage difference between the gate and source...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Multi-source machine learning for short-term influenza forecasting in Hunan Province, China: a spatiotemporal analysis using surveillance, search, meteorological and air-quality data.

BMC infectious diseases·2026

Same author

Amorphous High-Entropy Oxides With High-Valent Metal and Oxygen-Vacancy Pairs for Thermally Stable Catalytic Oxidation.

Advanced materials (Deerfield Beach, Fla.)·2026

Same author

Unlocking 27.3% perovskite photovoltaics by interface-locked dual-molecule contact.

Science advances·2026

Same author

Intimate Interaction Between Nucleic Acid and Conjugated Polymers in Organic Electrochemical Transistors Enables Ultrasensitive Biomarker Detection.

Advanced materials (Deerfield Beach, Fla.)·2026

Same author

Bridging the Gap: A Quantitative Framework Correlating Static and Dynamic Adsorption Capacities for VOCs Removal Prediction.

Environmental science & technology·2026

Same author

Comprehensive Investigation of the Bioenergetic Responses and Toxicological Mechanisms of Diclofenac to Earthworm <i>Eisenia fetida</i>.

Journal of agricultural and food chemistry·2026

Search research articles

Related Experiment Video

Updated: Jan 9, 2026

Sensing of Barrier Tissue Disruption with an Organic Electrochemical Transistor

Sensing of Barrier Tissue Disruption with an Organic Electrochemical Transistor

Published on: February 10, 2014

Organic Electrochemical Transistors in Tissue-Interfaced Bioelectronics.

Ruixiang Bai¹, Zeyu Zhao¹, Feng Yan¹

¹Department of Applied Physics, Research Center for Organic Electronics, The Hong Kong Polytechnic University, Hung Hom, Kowloon, Hong Kong, People's Republic of China.

Advanced Science (Weinheim, Baden-Wurttemberg, Germany)

|December 8, 2025

Summary

Organic electrochemical transistors (OECTs) offer unique advantages for tissue-interfaced bioelectronics. This review details OECT design, fabrication, and applications for stable, long-term biological integration.

Keywords:

biocompatibility biosensors bio‐tissue interfaces mechanical compliance organic electrochemical transistors (OECTs)

More Related Videos

Translating Extracellular Electron Transfer Activities with Organic Electrochemical Transistors

Translating Extracellular Electron Transfer Activities with Organic Electrochemical Transistors

Published on: January 31, 2025

In Vitro Multiparametric Cellular Analysis by Micro Organic Charge-modulated Field-effect Transistor Arrays

In Vitro Multiparametric Cellular Analysis by Micro Organic Charge-modulated Field-effect Transistor Arrays

Published on: September 20, 2021

Related Experiment Videos

Last Updated: Jan 9, 2026

Sensing of Barrier Tissue Disruption with an Organic Electrochemical Transistor

Sensing of Barrier Tissue Disruption with an Organic Electrochemical Transistor

Published on: February 10, 2014

Translating Extracellular Electron Transfer Activities with Organic Electrochemical Transistors

Translating Extracellular Electron Transfer Activities with Organic Electrochemical Transistors

Published on: January 31, 2025

In Vitro Multiparametric Cellular Analysis by Micro Organic Charge-modulated Field-effect Transistor Arrays

In Vitro Multiparametric Cellular Analysis by Micro Organic Charge-modulated Field-effect Transistor Arrays

Published on: September 20, 2021

Area of Science:

Bioelectronics
Materials Science
Biomedical Engineering

Background:

Organic electrochemical transistors (OECTs) are key for tissue-interfaced bioelectronics due to their ability to bridge ionic and electronic signaling.
Their mechanical compliance, biocompatibility, and signal amplification are crucial for integrating with dynamic biological tissues.

Purpose of the Study:

To provide a comprehensive review of recent advancements in OECTs for biological integration.
To summarize progress in OECT design, fabrication, and application for stable bio-electronic interfaces.

Main Methods:

Reviewing fundamental OECT working mechanisms and signal transduction advantages.
Discussing strategies for enhanced bio-tissue interfacing: molecular functionalization, interface control, and mechanical matching.
Examining OECT systems for skin-mounted and implantable applications, focusing on stability and biocompatibility.

Main Results:

OECTs demonstrate significant potential for stable, long-term integration with soft biological tissues.
Key strategies have been identified to improve bio-tissue interfacing, including molecular functionalization and mechanical matching.
Developments in OECT systems show promise for both wearable and implantable bioelectronic devices.

Conclusions:

OECTs are highly promising for advanced bioelectronic applications requiring seamless tissue integration.
Further research into biocompatibility, foreign body response mitigation, and minimally invasive operation is essential.
Continued exploration of OECTs will drive innovation in personalized medicine and diagnostics.