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Updated: May 6, 2026

Analysis of Gene Expression Changes in the Rat Hippocampus After Deep Brain Stimulation of the Anterior Thalamic Nucleus
Published on: March 8, 2015
[Deep Brain Stimulation: From History to Recent Advances]
1Department of Neurology, National Center of Neurology and Psychiatry.
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Deep brain stimulation (DBS) has been a common treatment for Parkinson's disease, tremors, and dystonia since its approval in Japan for movement disorders in 2000. In the EU and USA, DBS has been studied as a therapeutic option for depression, obsessive-compulsive disorder, Tourette syndrome, and cluster headache. DBS functions via a neurophysiological mechanism in movement disorders rather than pharmacological mechanisms. In this review, I have attempted to provide an overview of DBS from its history to the most recent information.

