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Updated: Jan 9, 2026
Controlled Photoredox Ring-Opening Polymerization of O-Carboxyanhydrides Mediated by Ni/Zn Complexes
Published on: November 21, 2017
Regioselective Markovnikov Hydroalkylation of Unactivated Alkenes Enabled by Photoredox/Nickel Dual Catalysis
Jie Gao1, Liu-Shuo Shi1, Xian-Chen He1
1College of Chemistry and Chemical Engineering, Central South University, Changsha 410083, P. R. China.
Abstract:
Developing practical strategies and a new reaction mode to access the versatile photocatalytic hydroalkylation of olefins with well-controlled regioselectivity remains highly desirable. Herein, we report a photoredox/nickel dual-catalyzed, regioselective hydroalkylation of unactivated alkenes by using toluene derivatives as alkyl sources, offering an efficient route for the selective construction of C(sp3)-C(sp3) bonds. This protocol features synthetic simplicity, avoidance of an external hydrogen source, and high regioselectivity, thereby expanding its potential utility in organic synthesis.
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