Related Experiment Video

Updated: Jun 25, 2026

Bilateral Common Carotid Artery Occlusion as an Adequate Preconditioning Stimulus to Induce Early Ischemic Tolerance to Focal Cerebral Ischemia
07:46

Bilateral Common Carotid Artery Occlusion as an Adequate Preconditioning Stimulus to Induce Early Ischemic Tolerance to Focal Cerebral Ischemia

Published on: May 9, 2013

30.1K

Efficacy of Carotid Artery Stenting Without Embolic Protection Device for Carotid Stenosis: A Retrospective Cohort

Seyedbahaadin Siroos1, Morteza Taheri, Aryoobarzan Rahmatian

  • 1Advanced Diagnostic and Interventional Radiology Research Center (ADIR), Tehran University of Medical Sciences, Tehran, Iran.

The Neurologist
|December 8, 2025
PubMed

Insights

Carotid artery stenting (CAS) effectively reduces carotid stenosis (CS), lowering stroke risk. This study suggests CAS without embolic protection devices (EPDs) offers comparable early outcomes, especially where EPDs are unavailable.

Area of Science:

  • Neurology
  • Interventional Cardiology
  • Vascular Surgery

Background:

  • Carotid stenosis (CS) is a significant risk factor for ischemic stroke.
  • Carotid artery stenting (CAS) is an alternative to carotid endarterectomy (CEA) for stroke prevention.
  • The use of embolic protection devices (EPDs) during CAS is debated.

Purpose of the Study:

  • To evaluate the effectiveness and safety of CAS in reducing stroke risk in patients with CS.
  • To assess early neurological complication rates associated with CAS performed without EPDs.

Main Methods:

  • Retrospective cohort study of 91 patients undergoing CAS for internal carotid artery (ICA) stenosis.
  • Exclusion of patients with concurrent intracranial stenosis, prior CEA, or incomplete data.
  • CAS performed without EPDs, followed by ICU monitoring and selective MRI.

Main Results:

  • Significant reduction in stenosis from 80.58% to 16.61% post-CAS.
  • Early neurological complications occurred in 5.4% of patients, with full recovery in most cases.
  • One death from intracranial hemorrhage and one hemiplegia case reported; no restenosis observed on follow-up ultrasound.

Conclusions:

  • CAS is effective in reducing CS and may aid in stroke prevention.
  • CAS without EPDs demonstrated acceptable early outcomes in this cohort.
  • Findings are relevant for centers with limited EPD access.
Abstract

Keywords:
CAScarotid arterycarotid artery stentingcarotid stenosisstentstroke

More Related Videos

A Murine Model of Stent Implantation in the Carotid Artery for the Study of Restenosis04:30

A Murine Model of Stent Implantation in the Carotid Artery for the Study of Restenosis

Published on: May 14, 2013

26.2K
A Magnetic Resonance Imaging-based Computational Protocol for Analysis of Plaque Morphology and Hemodynamics in Patients with Carotid Artery Stenosis09:36

A Magnetic Resonance Imaging-based Computational Protocol for Analysis of Plaque Morphology and Hemodynamics in Patients with Carotid Artery Stenosis

Published on: August 12, 2025

518

Related Concept Videos

Heart Failure Drugs: β-Blockers01:22

Heart Failure Drugs: β-Blockers

β-adrenergic antagonists, commonly known as β-blockers, block the effects of sympathetic neurotransmitters such as noradrenaline (NA) and adrenaline (ADR). They have several beneficial effects in heart failure treatment. They reduce heart rate, the force of contraction, and cardiac muscle relaxation. They also slow the atrial-ventricular conduction rate and raise the threshold for arrhythmias. The concentration of β-blockers determines their effects on bronchodilation, vasodilation, and...
Mitral Stenosis III: Medical Management01:26

Mitral Stenosis III: Medical Management

Mitral stenosis, a condition marked by the narrowing of the mitral valve, necessitates an integrated approach for effective management. This approach includes preventative measures, medical therapy, and surgical interventions to reduce symptoms and prevent complications.PreventionPrevention of mitral stenosis primarily focuses on reducing the incidence of bacterial infections, particularly streptococcal infections, which can lead to rheumatic fever and subsequent valvular damage. Timely...
Aortic Regurgitation III: Medical Management01:25

Aortic Regurgitation III: Medical Management

Aortic regurgitation (AR) is when the aortic valve does not close or seal properly, leading to backward blood circulation from the aorta into the left ventricle during diastole. Common causes of AR include rheumatic heart disease, congenital valve defects, and aortic root dilation. Managing AR requires a multifaceted approach to alleviate symptoms, preserve left ventricular function, and address the underlying cause of the regurgitation. Patients with symptomatic AR or significant left...