Related Experiment Video
Updated: Jan 9, 2026

Fracture Apparatus Design and Protocol Optimization for Closed-stabilized Fractures in Rodents
Published on: August 14, 2018
Prophylactic fixation in elderly fractures: Preventive breakthrough or unnecessary intervention?
Mohamed Sameer1, Sathish Muthu2,3, Srujun Vadranapu4
1Department of Orthopaedics, Sri Ramachandra Institute of Higher Education and Research, Chennai 600116, Tamil Nādu, India.
Abstract:
Prophylactic fixation (ProFix) of the proximal femur in elderly patients with osteoporosis presents a forward-thinking approach to preventing debilitating fractures and their associated complications. By addressing fracture risk before an injury occurs, ProFix has the potential to enhance patient outcomes, promote long-term mobility, and reduce healthcare costs. Early intervention in individuals at high risk can significantly lower hospital admissions, shorten recovery periods, and preserve independence, mitigating challenges such as chronic pain and reduced life expectancy. Given the high prevalence of undiagnosed osteoporosis, prioritising early risk assessment and targeted prevention is essential. Advancements in minimally invasive surgical techniques and safer anaesthesia methods further support ProFix as a feasible and effective strategy to decrease fracture-related morbidity, improve overall patient well-being, and optimise the use of healthcare resources. This opinion review details the evidence supporting this concept, its efficacy, the challenges in its implementation, and a strategic plan for future implementation.
More Related Videos
04:19Minimally Invasive Treatment for Thoracolumbar Burst Fracture Using Sagittal Alignment Screws and A Trauma Reduction Device
Published on: November 8, 2024
07:35Creating Rigidly Stabilized Fractures for Assessing Intramembranous Ossification, Distraction Osteogenesis, or Healing of Critical Sized Defects
Published on: April 11, 2012
Related Concept Videos
Fractures: Bone Repair
Minor fractures with no bone displacement are treated by immobilizing the fractured bone using a cast or splint. However, in the case of fractures with displaced bones, the broken bones are repositioned before immobilization to ensure successful healing without deformation and loss of function. The realignment of fractured bone ends is performed through a process called reduction. If the...
Bone Disorders
Bone deposition is also affected by the levels of sex hormones like estrogen and testosterone that promote osteoblast activity and bone matrix synthesis. When the level of these hormones decreases due to aging, it causes a reduction in bone deposition. As a result, bone resorption by osteoclasts...
Drug Dosing: Geriatric Patients
Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Distribution