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Berberine in diabetic nephropathy: mechanistic overview

Yang Yanru1, Cui Jia1, Yu Yan2

  • 1Gansu University of Chinese Medicine, Lanzhou, 730000 People's Republic of China.

Diabetology International
|December 8, 2025
PubMed
Summary

Berberine (BBR) shows promise for diabetic nephropathy (DN) by targeting multiple pathways. This natural compound alleviates inflammation, oxidative stress, and fibrosis, offering a potential new treatment for metabolic kidney disease.

Keywords:
BerberineDiabetic nephropathyMechanism of actionRenal function improvementSystematic review

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