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Related Experiment Video

Updated: Jan 9, 2026

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Development of a Nomogram to Classify In-Hospital Atrial Fibrillation Among Patients Hospitalized With Acute

Geng Yang1, Long Feng1, Yilin Pan1

  • 1Department of Emergency, Beijing Anzhen Hospital, Capital Medical University, 100029 Beijing, China.

Reviews in Cardiovascular Medicine
|December 8, 2025
PubMed
Summary

This study developed a nomogram model to predict atrial fibrillation (AF) in patients with acute myocardial infarction (AMI). The model, using easily obtainable clinical variables, demonstrated good predictive performance for personalized risk assessment.

Keywords:
acute myocardial infarctionatrial fibrillationprediction modelrisk factors

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Area of Science:

  • Cardiology
  • Medical Informatics
  • Clinical Prediction Models

Background:

  • Limited research exists on prognostic predictors for acute myocardial infarction (AMI) complicated by atrial fibrillation (AF).
  • A need for effective prognosis models for AMI-AF patients is evident.

Purpose of the Study:

  • To develop and validate a predictive model for atrial fibrillation (AF) in patients experiencing acute myocardial infarction (AMI).
  • To identify independent risk factors for AF in AMI patients.

Main Methods:

  • Retrospective analysis of 126 AMI patients with AF and 1719 AMI patients without AF.
  • Multivariate logistic regression and Receiver Operating Characteristic (ROC) curve analysis were used to identify predictors and evaluate model performance.
  • A nomogram model was constructed using R software, with calibration plots and Decision Curve Analysis (DCA) for validation.

Main Results:

  • Older age and longer hospitalization were identified as independent risk factors for AF in AMI patients.
  • The nomogram model achieved an Area Under the Curve (AUC) of 0.833, with 81.7% sensitivity and 72.6% specificity.
  • The model showed clinical utility for risk thresholds above 0.06.

Conclusions:

  • The developed multivariable prediction model, a nomogram, exhibits strong predictive capabilities for AF in AMI patients.
  • The variables utilized in the nomogram are readily accessible in clinical settings.
  • This model offers valuable insights for individualized AF risk prediction in AMI patients.