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Related Concept Videos

Aortic Regurgitation III: Medical Management01:25

Aortic Regurgitation III: Medical Management

375
Aortic regurgitation (AR) is when the aortic valve does not close or seal properly, leading to backward blood circulation from the aorta into the left ventricle during diastole. Common causes of AR include rheumatic heart disease, congenital valve defects, and aortic root dilation. Managing AR requires a multifaceted approach to alleviate symptoms, preserve left ventricular function, and address the underlying cause of the regurgitation. Patients with symptomatic AR or significant left...
375
Mitral Stenosis III: Medical Management01:26

Mitral Stenosis III: Medical Management

223
Mitral stenosis, a condition marked by the narrowing of the mitral valve, necessitates an integrated approach for effective management. This approach includes preventative measures, medical therapy, and surgical interventions to reduce symptoms and prevent complications.PreventionPrevention of mitral stenosis primarily focuses on reducing the incidence of bacterial infections, particularly streptococcal infections, which can lead to rheumatic fever and subsequent valvular damage. Timely...
223

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Related Experiment Video

Updated: Jan 9, 2026

Upper-extremity Approach for Secondary Access in Transfemoral Transcatheter Aortic Valve Implantation
06:04

Upper-extremity Approach for Secondary Access in Transfemoral Transcatheter Aortic Valve Implantation

Published on: August 8, 2025

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Transcatheter Aortic Valve Replacement in Special Population Groups.

Kameel Kassab1, Karnav Modi2, Christian Torres1

  • 1Division of Cardiology, Onvida Health, Yuma, AZ 85364, USA.

Reviews in Cardiovascular Medicine
|December 8, 2025
PubMed
Summary

Transcatheter aortic valve replacement (TAVR) is now used in special patient groups with severe aortic stenosis. This review examines TAVR

Keywords:
TAVRspecial populationstranscatheter aortic valve replacement

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Area of Science:

  • Cardiology
  • Interventional Cardiology
  • Cardiac Surgery

Background:

  • Transcatheter aortic valve replacement (TAVR) has transformed severe symptomatic aortic stenosis treatment across all surgical risk categories.
  • TAVR's application has expanded to unique populations, including those with active malignancies, psychiatric disorders, and advanced organ dysfunction, who were previously underrepresented in clinical trials.

Purpose of the Study:

  • To evaluate the safety, efficacy, and appropriateness of TAVR in special patient populations.
  • To identify specific challenges associated with TAVR implantation in these unique clinical groups.

Main Methods:

  • Comprehensive literature review of current studies on TAVR in special patient populations.
  • Analysis of existing data regarding outcomes and procedural considerations.

Main Results:

  • TAVR demonstrates feasibility and acceptable outcomes in patients with active malignancies, psychiatric disorders, and advanced organ dysfunction.
  • Specific challenges include managing comorbidities, multidisciplinary care coordination, and patient selection.

Conclusions:

  • TAVR is a viable option for selected patients with severe aortic stenosis and unique clinical considerations.
  • Further research is needed to optimize TAVR strategies and outcomes in these underrepresented groups.