Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

ECG Interpretation of Arrhythmias II: Atrial, Junctional and Ventricular Arrhythmias01:25

ECG Interpretation of Arrhythmias II: Atrial, Junctional and Ventricular Arrhythmias

433
Arrhythmia is a condition characterized by an irregular heart rhythm, with ECG changes that differ based on its origin and nature. The types of arrhythmias discussed below include atrial, junctional, and ventricular arrhythmias.Atrial ArrhythmiasPremature Atrial Complexes (PACs): PACs are early atrial beats caused by stress, caffeine, alcohol, electrolyte imbalances, hypoxia, hyperthyroidism, or certain medications (e.g., bronchodilators and decongestants). The ECG shows early P waves with an...
433
Electrocardiogram Fundamentals01:28

Electrocardiogram Fundamentals

1.4K
Introduction
An electrocardiogram (ECG) is a diagnostic tool for identifying cardiac conditions such as arrhythmias, conduction abnormalities, and myocardial ischemia.
Definition
An electrocardiogram (ECG) visualizes the heart's electrical activity by tracing the electrical movement associated with each heartbeat on a graph or monitor. As the heart beats, an electrical wave passes through it, correlating with the cardiac cycle events.
Parts of an ECG
An ECG utilizes electrodes on the skin...
1.4K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Side-viewing probe for lesion depth mapping on the left ventricle epicardium with near-infrared spectroscopy.

Scientific reports·2026
Same author

HRS position statement: Changing the tide in CPR and AED education for students in the United States.

Heart rhythm·2026
Same author

Three-dimensional visualization of arrhythmogenic substrate in mouse hearts using panoramic optical mapping and micro-computed tomography.

Nature cardiovascular research·2026
Same author

Double potential gradient analysis for critical isthmus detection in scar-related atrial tachycardia.

Heart rhythm·2026
Same author

Automated Detection of Macro-Reentrant Atrial Tachycardia Circuits Using LAT-Derived Graph Networks.

medRxiv : the preprint server for health sciences·2026
Same author

Sinus Rhythm Parameters in the Infarct Border Zone Are Useful to Assess Reentrant Ventricular Tachycardia Inducibility.

Journal of cardiovascular electrophysiology·2026

Related Experiment Video

Updated: Jan 9, 2026

High-Resolution Endocardial and Epicardial Optical Mapping in a Sheep Model of Stretch-Induced Atrial Fibrillation
09:17

High-Resolution Endocardial and Epicardial Optical Mapping in a Sheep Model of Stretch-Induced Atrial Fibrillation

Published on: July 29, 2011

15.2K

Atrial fibrillation substrate mapping with emphasis on voltage-based guidance.

Edward J Ciaccio1, Henry H Hsia2, Hirad Yarmohammadi3

  • 1Division of Cardiology, Department of Medicine, Columbia University Medical Center, New York, NY 10032, United States. ejc6@columbia.edu.

World Journal of Cardiology
|December 8, 2025
PubMed
Summary

Voltage substrate mapping aids atrial fibrillation (AF) treatment by identifying fibrosis. However, inconsistent data acquisition and analysis methods hinder its effectiveness and reproducibility.

Keywords:
AblationAtrial fibrillationSinus rhythmSubstrate mappingVoltage

More Related Videos

Ablation of Ischemic Ventricular Tachycardia Using a Multipolar Catheter and 3-dimensional Mapping System for High-density Electro-anatomical Reconstruction
06:57

Ablation of Ischemic Ventricular Tachycardia Using a Multipolar Catheter and 3-dimensional Mapping System for High-density Electro-anatomical Reconstruction

Published on: January 31, 2019

15.2K
Real-Time Cardiac Mapping with a Noninvasive Imageless Electrocardiographic Imaging System
10:17

Real-Time Cardiac Mapping with a Noninvasive Imageless Electrocardiographic Imaging System

Published on: April 11, 2025

1.5K

Related Experiment Videos

Last Updated: Jan 9, 2026

High-Resolution Endocardial and Epicardial Optical Mapping in a Sheep Model of Stretch-Induced Atrial Fibrillation
09:17

High-Resolution Endocardial and Epicardial Optical Mapping in a Sheep Model of Stretch-Induced Atrial Fibrillation

Published on: July 29, 2011

15.2K
Ablation of Ischemic Ventricular Tachycardia Using a Multipolar Catheter and 3-dimensional Mapping System for High-density Electro-anatomical Reconstruction
06:57

Ablation of Ischemic Ventricular Tachycardia Using a Multipolar Catheter and 3-dimensional Mapping System for High-density Electro-anatomical Reconstruction

Published on: January 31, 2019

15.2K
Real-Time Cardiac Mapping with a Noninvasive Imageless Electrocardiographic Imaging System
10:17

Real-Time Cardiac Mapping with a Noninvasive Imageless Electrocardiographic Imaging System

Published on: April 11, 2025

1.5K

Area of Science:

  • Cardiology
  • Electrophysiology
  • Medical Imaging

Background:

  • Atrial fibrillation (AF) treatment benefits from voltage substrate mapping to detect atrial fibrosis.
  • Low bipolar voltage areas indicate abnormal tissue and conduction, crucial for identifying substrate.
  • Electrophysiology mapping platforms enable rapid construction of atrial geometric models.

Purpose of the Study:

  • To describe and discuss voltage substrate mapping variables for AF and radiofrequency ablation.
  • To highlight challenges affecting mapping quality and reproducibility.
  • To suggest future research directions for standardization.

Main Methods:

  • Utilizing electroanatomic mapping platforms with bipolar electrodes to record atrial voltage data.
  • Projecting recording site coordinates onto an atrial shell with voltage data interpolation.
  • Analyzing bipolar electrogram amplitude on a 3D shell for substrate characterization.

Main Results:

  • Voltage substrate mapping reveals areas of low peak-to-peak voltage indicative of abnormal tissue.
  • Uncontrolled variables (wavefront direction, catheter angle, force, tissue structure) impact voltage measurements.
  • Current techniques for data acquisition and electrogram characterization lack standardization.

Conclusions:

  • Voltage substrate mapping is a valuable tool for AF management, particularly in identifying fibrotic substrate.
  • Standardization of mapping techniques and data analysis is essential for improving quality and reproducibility.
  • Further research is needed to refine methods for AF substrate characterization and radiofrequency ablation guidance.