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Related Concept Videos

Autoimmune Disorders01:29

Autoimmune Disorders

1.4K
Autoimmune diseases are a group of disorders in which the body's immune system mistakenly attacks its own cells, tissues, and organs. This results from an overactive immune response against substances and tissues normally present in the body. Let's delve into the concept and mechanism of autoimmune diseases from an immune system point of view, explore different causes and examples of such diseases, and discuss potential solutions.
Concept and Mechanism of Autoimmune Diseases
The immune...
1.4K
Myasthenia Gravis: Overview and Treatment01:20

Myasthenia Gravis: Overview and Treatment

2.7K
Myasthenia gravis is a neuromuscular transmission disorder characterized by weakness and increased fatigability of skeletal muscles. It is an autoimmune disease affecting approximately one in 2000 people, where antibodies against the α1 subunit of nicotinic acetylcholine receptors are produced.
These antibodies interfere with the function of the nicotinic receptors in three ways: by binding to the receptor and disrupting acetylcholine binding; by causing cross-linking of receptors which...
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Related Experiment Video

Updated: Jan 9, 2026

Anti-Nuclear Antibody Screening Using HEp-2 Cells
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Anti-Nuclear Antibody Screening Using HEp-2 Cells

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Autoimmune Nodopathy With Anti-Neurofascin 186 Antibody.

Ashik Anilkumar1, Parameswaran Krishnan2

  • 1Neurology, Indo American Hospital Brain and spine Center, Vaikom, IND.

Cureus
|December 8, 2025
PubMed
Summary

Autoimmune neuropathy, specifically anti-neurofascin 186 nodopathy, requires early antibody testing for effective treatment. Prompt diagnosis and targeted therapies like rituximab offer significant symptom relief.

Area of Science:

  • Neurology
  • Immunology
  • Clinical Case Study

Background:

  • Autoimmune neuropathy is a subclass of immune-mediated neuropathy characterized by specific antibody profiles.
  • Early identification of autoimmune neuropathy is critical for symptom management and improved patient outcomes.
Keywords:
anti-neurofascin 186 antibodyautoantibody profilingautoimmune nodopathyimmune-mediated neuropathyimmunotherapyrituximab therapy

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