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Spinal Cord: Cross-sectional Anatomy01:16

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The cross-sectional anatomy of the spinal cord offers a detailed view of its complex structure and function within the central nervous system. At the core of the spinal cord lies the gray matter, characterized by its butterfly or "H"-shaped appearance in cross-section. This central region is enveloped by white matter, with the overall structure divided into symmetrical halves by the dorsal median sulcus and the ventral median fissure.
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The spinal cord is the body’s major nerve tract of the central nervous system, communicating afferent sensory information from the periphery to the brain and efferent motor information from the brain to the body. The human spinal cord extends from the hole at the base of the skull, or foramen magnum, to the level of the first or second lumbar vertebra.
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The spinal cord, a critical component of the central nervous system, extends from the base of the brainstem to the lumbar region of the vertebral column. It is essential for maintaining physical stability and facilitating communication between the brain and peripheral parts of the body.
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Related Experiment Video

Updated: Jan 9, 2026

A Bioluminescent and Fluorescent Orthotopic Syngeneic Murine Model of Androgen-dependent and Castration-resistant Prostate Cancer
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Spinal Cord Infarction Following Zoledronic Acid Administration in a Patient With Metastatic Prostate Cancer.

Brittany E Reid1, Mario Perez2, Zakaria Abd Elmageed3

  • 1Rehabilitation Medicine, Independent Researcher, Chicago, USA.

Cureus
|December 8, 2025
PubMed
Summary

This case report details a rare spinal cord infarction in a patient with metastatic prostate cancer. It highlights potential vascular risks of bisphosphonates and the importance of rehabilitation for spinal cord injury.

Area of Science:

  • Neurology
  • Oncology
  • Rehabilitation Medicine

Background:

  • Spinal cord infarction is a rare complication associated with metastatic disease, radiation therapy, and vascular compromise.
Keywords:
bisphosphonatesmetastatic prostate cancerspinal cord infarctionspinal cord injuryzoledronic acid

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  • A 69-year-old male with metastatic prostate cancer experienced sudden onset paralysis and dysfunction following zoledronic acid infusion.