Prevalence of Peri-implant Diseases in Patients with Osteoporosis: a Systematic Review

This systematic review aimed to determine the prevalence of peri-implant diseases in patients affected by osteoporosis rehabilitated with dental implants.

An electronic search was conducted in the MEDLINE (PubMed), EMBASE, Scopus, and Web of Science databases up to April 2025, complemented by a manual search of the reference lists from the full-text studies. The search included observational studies that identified peri-implantitis and/or peri-implant mucositis in patients affected by osteoporosis rehabilitated with dental implants. The risk of bias was assessed using the Newcastle-Ottawa tool.

A total of 10, from 321, articles were included, and the reported evaluation periods after implant placement ranged from 3 to 11 years. Regardless of age, sex, number of implants, implant location, or duration of oral bisphosphonate use, all studies investigating the presence of mucositis and/or peri-implantitis reported no higher prevalence compared to systemically healthy patients. The prevalence of peri-implantitis was found to be 22%, and peri-implant mucositis 20%, in patients affected by osteoporosis.

Within the limits of this systematic review, it is concluded that osteoporosis does not increase the prevalence of peri-implant diseases or dental implant failure.