Utilization of normothermic machine perfusion in pediatric liver transplantation: Three case reports

Normothermic machine perfusion (NMP) utilizing OCS Liver is becoming increasingly common in adult liver transplantation (LT), but not in pediatric transplantation. OCS Liver has been shown to decrease post-reperfusion syndrome and early allograft dysfunction after transplantation. We describe the first case series of three pediatric patients who received a liver transplant using livers preserved with NMP.

Three pediatric patients, all with different etiologies of liver disease, were successfully transplanted with livers preserved with NMP. All patients are currently doing well with follow-ups of 7 to 16 months post-transplant.

The use of OCS Liver in pediatric LT is feasible and can be performed even in the sickest recipients with excellent outcomes. Utilization of OCS Liver can optimize donor and recipient factors to allow for optimal outcomes.