Massive breast fat necrosis with invasive breast cancer: A case report

Breast fat necrosis is a relatively uncommon benign breast condition, while invasive breast cancer is one of the most common types of breast cancer. Coexistence of massive breast fat necrosis with invasive breast cancer is relatively uncommon. The present study reported the case of a 74-year-old female patient who was diagnosed with breast cancer based on mammography findings; breast MRI indicated fat necrosis; subsequent surgical resection confirmed the coexistence of breast fat necrosis with invasive breast cancer using histopathological and immunohistochemical analysis. The relatively uncommon combination of these two conditions poses notable diagnostic challenges for radiologists. The present study reported relevant imaging findings to improve the understanding of radiologists on this disease, highlighting the clinical and radiological features.