Lung Cancer Outcomes in Vietnam: A 6-Year Retrospective Study
Khanh Toan Nguyen1, Thi Huong Pham1,2, Van Lam Ngo1
1Nghe An Oncology Hospital, Vinh, Nghe An Province, Vietnam.
Journal of Immunotherapy and Precision Oncology
|December 8, 2025
Summary
Lung cancer survival in Vietnam improved with increased early-stage diagnoses and personalized treatments. Key factors influencing mortality include advanced stage, male sex, and non-surgical initial treatment.
Area of Science:
- Oncology
- Epidemiology
- Public Health
Background:
- Lung cancer remains a significant health challenge globally and in Vietnam.
- Understanding patient demographics, treatment patterns, and survival is crucial for improving care.
Purpose of the Study:
- To document patient characteristics, treatment modalities, and survival outcomes for lung cancer patients in Vietnam.
- To analyze trends in diagnosis and treatment over a six-year period (2018-2024).
Main Methods:
- Retrospective study of 3548 lung cancer patients at Nghe An Oncology Hospital (2018-2024).
- Primary endpoints: treatment methods for non-small cell lung cancer (NSCLC) and small cell lung cancer (SCLC), and overall survival (OS).
- Secondary endpoints: factors influencing survival duration.
Main Results:
- NSCLC comprised 87% of cases, with adenocarcinoma being the most common subtype (67%).
- Early-stage diagnoses increased from 2.7% to 9%, while advanced stages decreased.
- Median OS was 15.3 months; 5-year survival was 14.2%. Stage IV NSCLC had 8.3% 5-year survival.
- Independent mortality factors included male sex, poor performance status, small cell histology, and metastatic disease.
Conclusions:
- Personalized treatment approaches are vital for improving lung cancer outcomes in Vietnam.
- Enhanced early detection and access to advanced therapies are urgently needed to reduce the lung cancer burden.
- Findings highlight the need for integrated public health strategies for lung cancer management.
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