Related Experiment Video

Updated: Jan 9, 2026

Quantification of the Immunosuppressant Tacrolimus on Dried Blood Spots Using LC-MS/MS
08:38

Quantification of the Immunosuppressant Tacrolimus on Dried Blood Spots Using LC-MS/MS

Published on: November 8, 2015

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Tacrolimus Conversion in CYP3A5*1 Expressers: From Immediate-Release to LCP Formulation

Anna Vidal-Alabró1, Pere Fontova1,2, Zeyar Mohammed Ali1,3

  • 1Nephrology Department, Hospital Universitari de Bellvitge-IDIBELL, Barcelona, Spain.

Therapeutic Drug Monitoring
|December 8, 2025
PubMed
Summary

CYP3A5 genetic variations impact tacrolimus (immunosuppressant) levels after switching formulations. Tacrolimus dose adjustments for kidney transplant patients should consider CYP3A5 genotype for optimal exposure control.

Keywords:
conversionkidney transplantationpharmacogeneticspharmacokineticstacrolimus

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