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Updated: Jan 9, 2026

In Vivo Imaging of Cerebrospinal Fluid Transport through the Intact Mouse Skull using Fluorescence Macroscopy

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Published on: July 29, 2019

Assessment of Cerebrospinal Fluid Flow Patterns Using Time-Spatial Labeling Inversion Pulse Sequence in a Dog With

Daisuke Ito¹, Chieko Ishikawa², Nick D Jeffery¹

¹Department of Small Animal Clinical Sciences, Texas A&M University, College Station, Texas, USA.

Veterinary Radiology & Ultrasound : the Official Journal of the American College of Veterinary Radiology and the International Veterinary Radiology Association

|December 8, 2025

Summary

This study shows how advanced imaging of cerebrospinal fluid (CSF) flow in toy poodles with syringomyelia can guide surgical treatment, leading to improved mobility and outcomes.

Area of Science:

Veterinary Neurology
Neurosurgery
Medical Imaging

Background:

Syringomyelia and Chiari-like malformation cause progressive neurological deficits in toy poodles.

Keywords:

cerebrospinal fluid (CSF)magnetic resonance imaging (MRI)syrinx time‐spatial labeling inversion pulse (Time‐SLIP)ventriculoperitoneal shunt

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Abnormal cerebrospinal fluid (CSF) flow dynamics are implicated in the pathogenesis of these conditions.

Accurate assessment of CSF flow is crucial for effective treatment planning.