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Sex-related presentation, outcome, and treatment in CICU: the SPOTlight STUDY
Alessia d'Aiello1,2, Mattia Brecciaroli1,2, Simone Filomia1,2
1Department of Cardiovascular and Pulmonary Sciences, Catholic University of the Sacred Heart, Rome, Italy.
Key Points:
WHAT IS ALREADY KNOWN: • Sex-related differences in cardiovascular disease presentation, management, and outcomes have been increasingly recognized in recent years. • Women with acute cardiovascular conditions often receive less aggressive diagnostic and therapeutic interventions compared to men, particularly in the setting of acute coronary syndromes.
What This Study Adds:
• This study provides a comprehensive evaluation of sex-related differences in a contemporary cohort of patients admitted to the Cardiac Intensive Care Unit (CICU), highlighting distinct admission patterns and management disparities. • Women with cardiovascular disease tend to be older at presentation, exhibit different risk factor profiles, and show distinct clinical manifestations compared to men. • It identifies higher mortality rates for women with STEMI and pulmonary embolism, emphasizing the need for improved recognition and tailored management of sex-specific differences in acute cardiovascular care.
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