Related Experiment Video
Updated: Jan 9, 2026

Author Spotlight: Evaluating Clinicians' Adoption of Ultrasound-Guided Vascular Cannulation Through Simulation Training
Published on: August 9, 2024
Assessing the Influence of a Statewide Dosing Reference Aid on Prehospital Pediatric Medication Dosing Errors: A
Bryan M Harmer1, John D Hoyle2, Autumn Edwards3
1Department of Paramedicine, College of Nursing, Creighton University, Omaha, Nebraska.
Prehospital pediatric medication errors persist despite a dosing reference aid. Common errors include incorrect weight, air in syringes, and improper dilution, indicating a need for improved strategies.
Area of Science:
- Emergency medicine
- Pediatric critical care
- Medication safety
Background:
- Prehospital pediatric medication administrations (PMA) have a high error rate (31%) in Michigan.
- Existing reference aids like MI-MEDIC may not fully address the root causes of these dosing errors.
Purpose of the Study:
- To investigate the frequency, magnitude, and immediate causes of PMA dosing errors.
- To evaluate the effectiveness of the MI-MEDIC pediatric dosing reference aid in reducing errors.
Main Methods:
- A mixed-method, simulation-based approach was used with emergency medical services (EMS) crews.
- High-fidelity simulations of pediatric emergencies were conducted, requiring medication administrations.
- Post-simulation interviews and a modified Delphi method were employed to analyze errors and their causes.
Main Results:
- Dosing errors occurred in 28.8% of administrations, with underdosing being more frequent (68.4%).
- Median underdose was 0.50, and median overdose was 2.00.
- Identified causes included incorrect weight (21%), air in syringes (31.6%), and improper medication dilution (31.6%) per the reference aid.
Conclusions:
- High rates of PMA dosing errors persist even with the MI-MEDIC reference aid.
- Current aids do not address critical error sources like incorrect weight, air in syringes, or dilution issues.
- Further research is needed to develop comprehensive strategies to mitigate identified active errors in pediatric medication safety.
More Related Videos
06:59A Novel Approach for the Administration of Medications and Fluids in Emergency Scenarios and Settings
Published on: November 9, 2016
09:52Setting Up a Stroke Team Algorithm and Conducting Simulation-based Training in the Emergency Department - A Practical Guide
Published on: January 15, 2017
Related Concept Videos
Drug Dosing: Infants and Children
Dosage Regimens: Designs and Approaches
Dosage Regimens: Partial Pharmacokinetic Parameters
Dose Size and Dosing Frequency: Determination Methods
Determination of Multiple Dosing Parameters: Loading and Maintenance Doses
Pharmacokinetics in Pediatric Patients: Drug Distribution