Consensus Opinion on Safe Injection Technique and Management of PDLLA-HA200-Induced Visual Impairment

Area of Science:

• Dermatology and Ophthalmology
• Aesthetic Medicine
• Injectable Materials Science

Background:

• Poly-D,L-lactic acid with hyaluronic acid (PDLLA-HA) is an advanced injectable filler.
• A rare but severe complication is vision loss from accidental intravascular injection.
• There is a critical need for standardized management protocols for this complication.

Purpose of the Study:

• To establish an expert consensus on safe practices for using PDLLA-HA 200 (Juvelook Volume/Lenisna).
• To develop a clinical management algorithm for PDLLA-HA-induced visual impairment and blindness.

Main Methods:

• Convening a panel of experts in oculoplastic surgery, dermatology, and aesthetic medicine.
• Reviewing existing literature and clinical experiences with PDLLA-HA injectables.
• Developing consensus guidelines and a management algorithm through expert deliberation.

Main Results:

• The consensus provides guidelines for safe injection techniques and immediate management strategies.
• A step-by-step algorithm is proposed for managing visual impairment and blindness following PDLLA-HA injection.
• Emphasis is placed on prompt recognition and intervention to mitigate visual damage.

Conclusions:

• Expert consensus is crucial for addressing rare but severe complications of PDLLA-HA injectables.
• The developed management algorithm aims to improve outcomes for patients experiencing visual impairment.
• Adherence to safe practices and established protocols can minimize the risk of blindness.