Comparing Etizolam and Music Distraction on Inferior Alveolar Nerve Block Success in Patients With Symptomatic
Anesthesia Progress
|December 8, 2025
Summary
Music distraction significantly improved inferior alveolar nerve block (IANB) success in anxious patients undergoing endodontic therapy. Etizolam did not offer a significant benefit over placebo for IANB success in this patient group.
Area of Science:
- Dentistry
- Anesthesiology
- Pain Management
Background:
- High dental anxiety is linked to increased pain during endodontic therapy.
- Effective local anesthesia is crucial for successful endodontic treatment, especially in anxious patients.
Purpose of the Study:
- To evaluate the efficacy of etizolam versus music distraction in improving inferior alveolar nerve block (IANB) success.
- To assess pain management during endodontic therapy in patients with high dental anxiety.
Main Methods:
- A randomized clinical trial involving 110 patients with symptomatic irreversible pulpitis.
- Patients were assigned to placebo, etizolam (0.5 mg), or music distraction (MD) groups.
- IANB success was measured by pain levels using the Heft Parker visual analogue scale (HP-VAS).
Main Results:
- Music distraction group showed significantly higher IANB success rates compared to placebo and etizolam groups (P < .01).
- No significant difference in IANB success was observed between the etizolam and placebo groups.
- Lower intraoperative pain was reported in the MD group.
Conclusions:
- Music distraction is a more effective strategy than etizolam or placebo for achieving IANB success in anxious patients.
- Non-pharmacological interventions like music can enhance dental anxiety management and treatment outcomes.
- Further research may explore combined approaches for optimal pain control.


