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Rac1 selectively binds a specific lamellipodin isoform via a noncanonical helical interface

Tong Gao1, Pingfeng Zhang1, Alison M Kurimchak1

  • 1Cancer Signaling and Microenvironment Program, Fox Chase Cancer Center, Philadelphia, Pennsylvania, USA.

The Journal of Biological Chemistry
|December 8, 2025
PubMed
Abstract

Keywords:
GTPase effectorRAPHRac1cell migrationisoformlamellipodinsplicing variant

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