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Updated: Jan 9, 2026

The MODS method for diagnosis of tuberculosis and multidrug resistant tuberculosis
Published on: August 11, 2008
Multidrug-resistant tuberculosis of the knee: A case report describing challenges in diagnosis and treatment
Vikar Singh1, Afsana Kajee2, Keeren Lutchminarain1
1Department of Microbiology, National Laboratory Health Services, KwaZulu-Natal Academic Complex, Inkosi Albert Luthuli Central Hospital, Durban, South Africa; Department of Medical Microbiology, School of Laboratory Medicine and Medical Science, College of Health Sciences, University of KwaZulu-Natal, Durban, South Africa.
Abstract:
Multidrug-resistant tuberculosis (MDR-TB) of osteoarticular sites poses significant diagnostic and therapeutic challenges. Rapid diagnosis and targeted treatment are critical to managing drug-resistant cases effectively, especially in limited-resourced settings with high TB burden. We describe a rare case of MDR-TB of the knee in an adult female patient who was successfully treated with an individualized exclusive oral multidrug regimen for 18 months.
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