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Pure Retroperitoneal Robot-Assisted Radical Nephroureterectomy (RANU): Initial Experience Using the Hinotori Surgical
Yuichiro Konnai1, Kazuhiro Matsumoto1, Keishiro Fukumoto1
1Department of Urology, Keio University School of Medicine, Tokyo, Japan.
Asian Journal of Endoscopic Surgery
|December 8, 2025
Summary
Pure retroperitoneal robot-assisted nephroureterectomy (RANU) using the hinotori system is safe for smaller patients with upper tract urothelial carcinoma (UTUC). This minimally invasive technique offers a viable alternative to traditional approaches.
Area of Science:
- Urology
- Surgical Oncology
- Robotic Surgery
Background:
- Upper tract urothelial carcinoma (UTUC) frequently necessitates nephroureterectomy.
- The retroperitoneal robotic approach, especially with the hinotori system, presents potential benefits for smaller patients.
Purpose of the Study:
- To evaluate the safety and feasibility of pure retroperitoneal robot-assisted nephroureterectomy (RANU) using the hinotori system in patients with UTUC.
- To assess outcomes such as operative time, re-docking, and complications in this patient cohort.
Main Methods:
- A cohort of five UTUC patients (≤162 cm) underwent pure retroperitoneal RANU with the hinotori system.
- Standardized trocar placement was employed without port relocation.
- Key outcomes monitored included operative duration, re-docking time, and any intraoperative or postoperative complications.
Main Results:
- All five procedures were successfully completed without peritoneal entry, conversion to open surgery, or major complications.
- The mean operative time was 257 minutes, with an average re-docking time of 18 minutes.
- All patients achieved negative surgical margins, and no 30-day readmissions were recorded.
Conclusions:
- Pure retroperitoneal RANU with the hinotori system is a safe and feasible option for UTUC treatment, particularly in smaller-framed individuals.
- This approach minimizes procedural interference and may be a valuable alternative to transperitoneal nephroureterectomy.
- Further research is warranted to validate oncological outcomes and optimize surgical techniques.

