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Flow cytometry-based targeted diagnostics for rapid assessment of daunorubicin resistance in acute myeloid leukemia

Aleksandra Kaczorowska1, Przemysław Sareło2,3, Marlena Gąsior-Głogowska2

  • 1Department of Biomedical Engineering, Faculty of Fundamental Problems of Technology, Wrocław University of Science and Technology, Wybrzeże Wyspianskiego 27, 50-370, Wrocław, Poland. aleksandra.kaczorowska@pwr.edu.pl.

Scientific Reports
|December 8, 2025
PubMed
Abstract

No abstract available in PubMed .

Keywords:
Acute myeloid leukemiaDaunorubicin resistanceDrug response testingEx vivo cultureFlow cytometry assayPrecision medicine

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Flow Cytometry01:23

Flow Cytometry

The development of flow cytometry techniques began in 1934 with initial attempts by Andrew Moldavan, a bacteriologist who counted the cells in a flowing capillary system. Moldavan pumped cells through a capillary tube focused under a microscope for visualization. The invention of photometry allowed the measurement of differentially-stained cells, and Louis Kamentsky developed the first multiparameter flow cytometer in 1965 to identify and count the cancer cells in cervical tissue specimens.
In...