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Updated: Jan 9, 2026

Tumor Engraftment in a Xenograft Mouse Model of Human Mantle Cell Lymphoma
Published on: March 30, 2018
[Endotracheal mantle cell lymphoma: a case report]
1Shandong Public Health Clinical Center, Public Health Clinical Center Affiliated to Shandong University, Jinan 250102, China.
Abstract:
Mantle cell lymphoma (MCL) is a subtype of B-cell non-Hodgkin lymphoma, typically diagnosed at an advanced stage with frequent extranodal involvement. Common sites of infiltration include the gastrointestinal tract, eye, liver, spleen, bone marrow, and central nervous system; however, pulmonary involvement-particularly tracheobronchial manifestation-is exceedingly rare. We report the case of a 60-year-old woman presenting with a 4-month history of cough and progressive dyspnea. Chest CT revealed a polypoid mass arising from the left tracheal wall, causing significant luminal narrowing. Under general anesthesia, bronchoscopic biopsy and tumor resection were performed, with histopathological examination confirming MCL.

