Related Experiment Video

Updated: Jan 9, 2026

Fully Endoscopic Mitral Valve Repair with Percutaneous Cannulation of Groin Vessels
08:12

Fully Endoscopic Mitral Valve Repair with Percutaneous Cannulation of Groin Vessels

Published on: May 26, 2023

2.2K

Long-term outcomes of infant mitral valve surgery

Segolene Bernheim1,2, Margaux Pontailler1, Alexander Moiroux-Sahraoui3

  • 1Department of Pediatric Cardiac Surgery, Pediatric Cardiac Intensive Cardiac Unit, Hôpital Necker-Enfants Malades, Assistance Publique - Hôpitaux de Parishttps://ror.org/05tr67282, Paris, France.

Cardiology in the Young
|December 9, 2025
PubMed

Insights

Mitral valve repair in infants shows better survival than replacement, though re-intervention is common for both. Surgery for congenital mitral valve disease under one year is high-risk, with repair delaying but not always preventing future valve replacement.

Area of Science:

  • Pediatric Cardiology
  • Congenital Heart Disease
  • Cardiac Surgery

Background:

  • Infants with mitral valve disease require surgical intervention.
  • Congenital mitral valve disease encompasses stenosis, regurgitation, or mixed pathologies.
  • Surgical options include mitral valve repair or replacement.

Purpose of the Study:

  • To evaluate patient outcomes after mitral valve repair or replacement in infants under one year of age.
  • To compare mortality and re-intervention rates between mitral repair and replacement.
  • To assess long-term survival and the need for subsequent interventions.

Main Methods:

  • Monocentric retrospective study of 56 infants undergoing mitral valve surgery (repair or replacement) before one year of age.
  • Data collected over 22 years (2001-2023).
  • Outcomes assessed included early and late mortality, and re-intervention rates.

Main Results:

  • Mitral valve repair was performed in 39 patients, and replacement in 17.
  • Replacement group had longer ICU/hospital stays and ventilation times, with higher early mortality (12% vs. 0%).
  • Survival was significantly higher in the repair group (p=0.039). Re-intervention was needed in 41.1% of patients, with re-intervention-free survival rates at 10 years of 46% for repair and 55% for replacement.

Conclusions:

  • Mitral valve surgery in infants is high-risk with a significant need for re-intervention.
  • Mitral repair offers superior short-term survival outcomes compared to replacement.
  • While repair may delay, it does not always prevent the eventual need for valve replacement.
Abstract

Keywords:
Mitral valve repaircongenital mitral valve diseaseinfantmitral valve replacementpaediatric cardiac surgery

More Related Videos

A Simplified Stepwise Approach to Echo Guidance during Percutaneous Mitral Valve Repair08:31

A Simplified Stepwise Approach to Echo Guidance during Percutaneous Mitral Valve Repair

Published on: October 16, 2021

4.3K
A Rodent Model of The Ross Operation: Syngeneic Pulmonary Artery Graft Implantation in A Systemic Position11:20

A Rodent Model of The Ross Operation: Syngeneic Pulmonary Artery Graft Implantation in A Systemic Position

Published on: April 1, 2022

3.4K

Related Concept Videos

Mitral Stenosis III: Medical Management01:26

Mitral Stenosis III: Medical Management

Mitral stenosis, a condition marked by the narrowing of the mitral valve, necessitates an integrated approach for effective management. This approach includes preventative measures, medical therapy, and surgical interventions to reduce symptoms and prevent complications.PreventionPrevention of mitral stenosis primarily focuses on reducing the incidence of bacterial infections, particularly streptococcal infections, which can lead to rheumatic fever and subsequent valvular damage. Timely...
223
Mitral Stenosis I: Introduction01:22

Mitral Stenosis I: Introduction

Mitral Valve Stenosis (MVS) is a heart condition where the mitral valve narrows, impeding blood circulation from the left atrium to the left ventricle. The etiology and pathophysiology of this condition are multifaceted, leading to a cascade of cardiovascular complications.Causes of Mitral Valve StenosisRheumatic Heart Disease: It is the main cause of mitral valve stenosis, particularly in developing nations. This condition arises from rheumatic fever, an inflammatory illness resulting from...
398
Mitral Stenosis IV: Nursing Management01:27

Mitral Stenosis IV: Nursing Management

A comprehensive nursing assessment is essential for patients with valvular heart disease, which involves any dysfunction of the heart valves that could impact blood flow and overall heart function.Subjective Data Collection:Chief Complaint and Present Illness: Start with the patient's primary concerns, focusing on the onset, duration, and progression of cardiac symptoms such as dyspnea, fatigue, chest pain, and palpitations.Past Medical History: Collect detailed information on any previous...
234
Mitral Valve Prolapse III: Nursing Management01:19

Mitral Valve Prolapse III: Nursing Management

The nursing management of Mitral Valve Prolapse, or MVP, centers around patient education, symptom monitoring, and lifestyle modifications.Patient Education on MVP Diagnosis and Heredity: Nurses should provide comprehensive education about MVP, a condition where the mitral valve does not close appropriately during heartbeats. This education often includes the condition's pathophysiology, symptoms, and potential complications, like arrhythmias or mitral regurgitation. Though not fully...
266
Mitral Stenosis II: Clinical features and Diagnostic Tests01:23

Mitral Stenosis II: Clinical features and Diagnostic Tests

Mitral stenosis is a heart condition in which the mitral valve, which allows blood to flow from the left atrium to the left ventricle, becomes narrowed or stenotic. This narrowing hinders blood flow and leads to clinical symptoms requiring specific medical evaluations and management strategies. The following overview outlines the clinical symptoms, assessments, diagnostic findings, prevention methods, and treatments for mitral stenosis.Clinical ManifestationsDyspnea (shortness of breath): This...
196
Mitral Regurgitation IV: Nursing Management01:28

Mitral Regurgitation IV: Nursing Management

Mitral regurgitation (MR) is a condition where the mitral valve does not close properly, leading to the backward flow of blood from the left ventricle into the left atrium during systole. This condition can arise from various causes, including rheumatic fever, infective endocarditis, or degenerative valve disease. Effective nursing management is crucial to optimizing patient outcomes and involves comprehensive assessment and targeted interventions.Comprehensive Patient AssessmentA detailed...
287