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Infantile Acute Myeloid Leukemia Presenting As Intussusception: A Case Report and Review of the Literature

Yuanyuan Gu1, Christopher Blackmore2, Kathryn McFadden3

  • 1Department of Pathology and Laboratory Medicine, Queen Elizabeth II Health Sciences Centre, Dalhousie University, London, CAN.

Cureus
|December 9, 2025
PubMed

Insights

A rare case of myeloid sarcoma (MS) presenting as bowel intussusception in an infant was successfully treated with chemotherapy. The child achieved remission, highlighting a treatable presentation of acute myeloid leukemia (AML).

Area of Science:

  • Pediatric Oncology
  • Hematology
  • Surgical Gastroenterology

Background:

  • Intussusception is a common cause of acute abdominal pain in infants.
  • Myeloid sarcoma (MS), a rare extramedullary manifestation of acute myeloid leukemia (AML), can present with diverse symptoms.
  • Bowel intussusception as a primary presentation of pediatric MS is exceptionally rare.

Keywords:
acute myeloid leukemia (aml)intussusceptionmyeloid sarcomapediatricsmall bowel malignancy

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